Preface

I. EPIDEMIOLOGY AND OVERVIEW

1. Type 1 Diabetes Mellitus: An Overview SALEH ADI AND ANDREA GERARD GONZALEZ

2. Prediabetes: Prevalence, Pathogenesis, and Recognition of Enhanced Risk ALOK K. GUPTA, AJAY MENON, MEGHAN BRASHEAR AND WILLIAM D. JOHNSON

3. Targeting Prediabetes to Preempt Diabetes SREEDHARAN N, MAHADEV RAO AND SONAL SEKHAR M

4. Obesity and Type 2 Diabetes in Youths: New Challenges to Overcome NICOLA SANTORO, COSIMO GIANNINI AND SONIA CAPRIO

5. Roles of Environmental Pollution and Pesticides in Diabetes and Obesity: The Epidemiological Evidence CHARLES J. EVERETT, DANIRA MEDUNJANIN AND IVAR L. FRITHSEN

6. An Overview of the Roles of the Gut Microbiome in Obesity and Diabetes GILLIAN M. BARLOW, EUGENIA A. LIN AND RUCHI MATHUR

II. TYPES OF DIABETES AND ITS CORRELATION WITH OTHER DISEASES

1. Role of Peripheral Neuropathy in the Development of Foot Ulceration and Impaired Wound Healing in Diabetes Mellitus FRANCESCO TECILAZICH AND ARISTIDIS VEVES

2. The Association of Diabetes in the Onset of Dementia in the Elderly Population: An Overview ABHAI KUMAR AND SMITA SINGH

3. The Role of Insulin Resistance in the Cardiorenal Syndrome ADAM WHALEY-CONNELL AND JAMES R. SOWERS

4. An Overview on Diabetic Nephropathy KEI FUKAMI AND SHO-ICHI YAMAGISHI

5. An Overview of Diabetic Retinopathy SHINTARO NAKAO, SHIGEO YOSHIDA AND KOH-HEI SONODA

6. An Overview of Gestational Diabetes CHRISTOPHER FEDERICO AND GABRIELLA PRIDJIAN

7. Diabetes, a Potential Threat to the Development and Progression of Tumor Cells in Individuals SAYANTAN MAITRA, STABAK DAS AND PRADIPTA BANERJEE

III. MOLECULAR INSIGHTS OF DIABETES AND METABOLIC SYNDROME

1. Lipid-Induced Insulin Resistance: Molecular Mechanisms and Clinical Implications SATINATH MUKHOPADHYAY, DEEP DUTTA AND DIPYAMAN GANGULY

2. Gene-Environment Interaction in the Pathogenesis of Type 2 Diabetes KIAN-PENG GOH

3. Renal Sodium-Glucose Transporter-2 Inhibitors and Antidiabetic Agents ANAND S. NAIR, DEBASIS BAGCHI AND SREEJAYAN NAIR

4. Emerging Role of MicroRNA in Diabetes Mellitus ANAND S. NAIR AND DEBASIS BAGCHI

IV. PATHOPHYSIOLOGY

1. Insulin Resistance Syndrome: A Crucial Example Where a Physiological Continuum of Risks Needs Attention HARRY G. PREUSS

2. Sleep Disturbances, Hypertension, and Type 2 Diabetes MICHELLE A. MILLER AND FRANCESCO P. CAPPUCCIO

3. Roles of Pancreatic Cell Function, Liver, Skeletal Muscle, and Adipose Tissue in Diabetes and the Metabolic Syndrome BEVERLY S. MÜHLHÄUSLER

4. Glycemic Variability and Its Clinical Implications NARSINGH VERMA

5. Diabetic Wound Inflammation SCOTT CHAFFEE, AMITAVA DAS, SUMAN SANTRA AND SASHWATI ROY

6. Sarcopenia, Diabetes, and Nutritional Intervention SHEILA M. WICKS, IVAN SALAMON, ANGELA I. CALDERON, ESPERANZA CARCACHE DE BLANCO AND GAIL B. MAHADY

V. PREVENTION AND TREATMENT 1: DIET, EXERCISE, SUPPLEMENTS AND ALTERNATIVE MEDICINES

1. Dietary Polyphenols, Gut Microbiota, and Intestinal Epithelial Health MEIJUN ZHU

2. Reducing the Risk of Diabetes and Metabolic Syndrome With Exercise and Physical Activity DAWN BLATT AND CHERI L. GOSTIC

3. Nutraceutical Impact on the Pathophysiology of Diabetes Mellitus ODETE MENDES, LEE KOETZNER AND JAYSON CHEN

4. Therapeutic Effect of Fucoxanthin on Metabolic Syndrome and Type 2 Diabetes KAZUO MIYASHITA, SHOW NISHIKAWA AND MASASHI HOSOKAWA

5. Safety and Antidiabetic Efficacy of a Novel Trigonella foenum-graecum Seed Extract ANAND SWAROOP, MANASHI BAGCHI, HARRY G. PREUSS AND DEBASIS BAGCHI

6. Beneficial Effects of Chromium(III) and Vanadium Supplements in Diabetes JOHN B. VINCENT

7. Protective Role of Alpha-Tocopherol in Diabetic Nephropathy DAIKI HAYASHI AND YASUHITO SHIRAI

8. Antidiabetic Activity of Curcumin: Insight Into Its Mechanisms of Action MARZENA WOJCIK, MICHAL KRAWCZYK AND LUCYNA A. WOZNIAK

9. Meal Plans for Diabetics: Caloric Intake, Calorie Counting, and Glycemic In